Nis-Nest Database

Department of Cellular Membranology (DEPTCM)
   
Organisation Type: Research
Email: krishtal@biph.kiev.ua
Address: 4 Bogomoletz str.
Region: Kiev
Country: UKRAINE
Phone: +380442532466
Fax: +380442562590
Web Address: http://www.deptcm.kiev.ua
   
Parent Organisation: Bogomoletz Institute of Physiology
Children Organisations: --
   
Research/Thematic Area:
  • Biotechnology, generic tools and medical technologies for human health
  • Other Actions across the health theme
  • Nanosciences, Nanotechnologies
  • Initial training of researchers
  • Life-long training and career development
  • Research for SMEs
  • International co-operation
  • Specific Programme Ideas to support basic, frontier research
   
Scientific Domains:
  • BIOTECHNOLOGY
  • EDUCATION, TRAINING
  • LIFE SCIENCES
  • MEDICINE, HEALTH
  • SCIENTIFIC RESEARCH
Number of senior researchers 9
Number of phD students 6
   
Authorized person Full Name: Krishtal Oleg
Position: Head of the Department
Gender: Male
   
Number of publications (since 1998) 72
Major Publications 1. Krishtal, O. “The ASICs: Signaling molecules? Modulators?” (2003) Trends in Neurosciences, 26 (9), pp. 477-483 2. Pankratov, Y.V., Lalo, U.V., Krishtal, O.A. “Role for P2X receptors in long-term potentiation” (2002) Journal of Neuroscience, 22 (19), pp. 8363-8369. 3. Pankratov, Y., Lalo, U., Krishtal, O., Verkhrastsky, A. “Ionotropic P2X purinoreceptors mediate synaptic transmission in rat pyramidal neurones of layer II/III of somato-sensory cortex” (2002) Journal of Physiology, 542 (2), pp. 529-536. 4. Chatterjee, S., Filippov, V., Lishko, P., Maximyuk, O., No?ldner, M., Krishtal, O. “Hyperforin attenuates various ionic conductance mechanisms in the isolated hippocampal neurons of rat” (1999) Life Sciences, 65 (22), pp. 2395-2405. 5. Pankratov, Y., Castro, E., Miras-Portugal, M.T., Krishtal, O. “A purinergic component of the excitatory postsynaptic current mediated by P2X receptors in the CA1 neurons of the rat hippocampus” (1998) European Journal of Neuroscience, 10 (12), pp. 3898-3902.
Participation in EU projects (since 1994 ) 2007-2009 Research grant INTAS 05-1000008-7843 “Opioids and cannabinoids: effects on synaptic plasticity via novel molecular targets” (Co-ordinator Prof. Alexei Verkhratsky) 2002-2004 Research grant INTAS 011-0651 “The function of acid-sensing ionic channels in nociception” (Co-ordinator Dr. Carlos M. Belmonte) 2000-2002 Research grant INTAS-99-01147 “Purinergic modulation of synaptic transmission in central and peripheral nervous system” (Co-ordinator Prof. F. Edwards). 1998-2002 Wellcome Trust Collaborative Research Initiative Grant DRDB “Extrasynaptic actions of glutamate at NMDA receptors” 1998-2001 Research grant INTAS-96-1493 “NMDA receptor-mediated positive feedback in excitatory input to CA1 pyramidal neurons: electrophysiological and pharmacological approach to ischemia and epilepsy” (Co-ordinator Prof. U. Heinemann) 1996 CEEC/NIS joint research project (NF 7UKPJ048607) entitled “Separate regulation of NMDA and non-NMDA components of the excitatory synaptic transmission in hippocampus: possible role of various endogenous agonists” supported by Swiss National Science Foundation. 1995-1997 Research grant INTAS-94-0849 entitled “Excitatory Synaptic Transmission in Hippocampus: Regulation by calcium channels” (Co-ordinator. Prof. M. Klee) 1995-1997 Research grant INTAS-94-4072 “Properties and regulation of hippocampal NMDA receptors” (Co-ordinator. Prof. A. Konnerth). 1994-1995 Research grant INTAS-93-0822 “Adenosine and endogenous adenine dinucleotides, approach to function and pharmacology in mammalian nervous system” (Co-ordinator. Prof. T. Peters)
Participation in national programmes/Projects (since 1994) 2006-2008 NAS Research Project “Mechanisms of regulation of pain signal by cascades of intracellular protein kinases activated by G-proteins” 2005-2007 NAS Research Project “Receptor mediated mechanisms of peripheral antinociception” 2004-2007 NAS Research Project “The search of effective influences on molecular mechanisms determining cells excitability” 2004-2006 NAS Research Project “The role of G-proteins in modulation of voltage gated calcium ion channels in central neurons” 2003-2005 NAS Research Project “Molecular mechanisms of genome functioning that determine specificity of functions of physiological systems in norm and pathology” 2002-2004 NAS Research Project “The role of the proton-, ATP-, capsaicin-gated channels in nociception” 2000-2003 NAS Research Project “Pharmacology and voltage dependence of voltage- and ligand gated channels and their participation in processes underlying synaptic transmission at hippocampus under normal and pathological conditions” 1999-2002 NAS Research Project “Molecular mechanisms of modulation of the synaptic transmission in the hippocampus” 1998-2001 NAS Research Project “Modulation of ligand gated channels in central neurons at normal and pathological conditions” 1997-1999 NAS Research Project “Pharmacological modulation of synaptic transmission in rat hippocampus: effective strategy against an ischemic damage of brain”